Principles and practice of hormetic treatment of aging and age-related diseases

Suresh IS Rattan
SAGE Publications
June 3, 2008

Aging is characterized by stochastic accumulation of molecular damage, progressive failure of maintenance and repair, and consequent onset of age-related diseases. Applying hormesis in aging research and therapy is based on the principle of stimulation of maintenance and repair pathways by repeated exposure to mild stress. Studies on the beneficial biological effects of repeated mild heat shock on human cells in culture, and other studies on the anti-aging and life-prolonging effects of proxidants, hypergravity, irradiation and ethanol on cells and organisms suggest that hormesis as an antiaging and gerontomodulatory approach has a promising future. Its clinical applications include prevention and treatment of diabetes, cataract, osteoporosis, dementia and some cancers.

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Principles and practice of hormetic treatment of aging and age-related diseases

(Jun. 3, 2008) Aging is characterized by stochastic accumulation of molecular damage, progressive failure of maintenance and repair, and consequent onset of age-related diseases. Applying hormesis in aging research and therapy is based on the principle of stimulation of maintenance and repair pathways by repeated exposure to mild stress. Continue reading

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Riding the rails means parking the cars

Heather Douglas
Canwest News Service
June 1, 2008

The World Madness Institute’s Transportation Division recently released a report claiming that most North American commuters are huge supporters of public transit — for others, not themselves.

The surveyors interviewed 10,000 people and discovered that 77 per cent of Americans and 89 per cent of Canadians wanted their municipal governments to either introduce or expand their local light rail transit system. They were almost unanimous in wanting to get everyone else’s cars off the road to cut their own travel times.

The study proves a global trend — more people drive and fewer take public transit — yet they universally think everyone else should “do their bit to save the environment and conserve energy.”

The glaring exception is London, England. Since 2000, 45 per cent more people ride transit daily and 10 per cent have stopped driving altogether. According to the London Transit Authority, they accomplished this while slashing subsidies, privatizing most of the city bus lines, and deregulating the underground through a series of public-private partnerships. They cut crime by installing on-board video cameras and boosting the surveillance monitoring of platforms and transfer stations. In short, their system flourishes in a free-market environment.

After all, “public transit is not inherently inferior to the private automobile; it can out-compete the car when and where market forces reign,” says Lawrence Solomon, Toronto Sprawls (2007).

The Calgary Chamber of Commerce suspects most Calgarians want city hall to expand our light rail transit (LRT). And, like the general population, our members complain a barrel of crude oil sells for about $130 and no level of government wants to lower the high taxes paid at the pumps.

Like the rest of the country, Calgarians want world-class transit. Most applaud the notion of getting people out of their cars and relieving the traffic congestion. Yet when city hall recently introduced its best option for the west leg of the LRT, many were opposed and NIMBYism (not-in-my-backyard) raised its head.

Every LRT expansion has seen citizens unhappy with proposed routes, the lack of transparent consultation, the noise, and the alleged decline in property values. In actuality, once the lines were built property values increased. Neighbourhoods appreciate their transit stops and view them as assets to their communities.

The chamber believes that new LRT lines are often derailed by local opposition despite the fact these major infrastructure projects are valuable to the entire city. These land-use decisions are inherently political and frequently determine the popularity of the local alderman.

According to the chamber’s research, particularly contentious zoning applications often take twice as long to be approved as non-politicized applications. Therefore, the city recommends the applicant always undertake extensive community and aldermanic consultation before submitting the application.

Ideally, council’s involvement in the approval process is to set broad policy direction, similar to the structures of the federal and provincial governments. Practically however, the aldermen are often directly involved in approving the land use and zoning applications for their constituents.

Perhaps city hall places too much emphasis on local community consultation (which is important) and ignores the input of citizens from every other community who might park their cars and take transit into the area to work, shop, learn, or play.

After much consideration, the chamber recommends council:

* Develop a set of citywide consultation protocols for all major land use applications to ensure bigger picture impacts are considered along with local ones.

* Weigh the valuable contribution from local community groups within the framework of a metropolis consultation and context.

* Create an electoral reform commission to review the current ward system and investigate moving to a mixed representation model in which council is composed of both ward aldermen and citywide aldermen.

The chamber applauds city hall’s verdict to move forward with the west leg of the LRT. The impacted communities need this infrastructure. It’s also the right decision for Calgary.

With worsening traffic snarls, more smog and escalating gas prices, now is the time to build affordable, efficient public transportation.

Maybe Calgary, like London, can convince more people to park their cars and ride the rails. If the World Madness Institute polled our citizens in a decade would they discover that 89 per cent of Calgarians supported the use of mass transit for themselves?

Heather Douglas is president & CEO of the Calgary Chamber of Commerce For more information on the Chamber’s public transportation recommendations, please see www.calgarychamber.com.

Posted in Energy Probe News, Privatization | Leave a comment

Riding the rails means parking the cars

Heather Douglas
Canwest News Service
June 1, 2008

The World Madness Institute’s Transportation Division recently released a report claiming that most North American commuters are huge supporters of public transit — for others, not themselves.

The surveyors interviewed 10,000 people and discovered that 77 per cent of Americans and 89 per cent of Canadians wanted their municipal governments to either introduce or expand their local light rail transit system. They were almost unanimous in wanting to get everyone else’s cars off the road to cut their own travel times.

The study proves a global trend — more people drive and fewer take public transit — yet they universally think everyone else should “do their bit to save the environment and conserve energy.”

The glaring exception is London, England. Since 2000, 45 per cent more people ride transit daily and 10 per cent have stopped driving altogether. According to the London Transit Authority, they accomplished this while slashing subsidies, privatizing most of the city bus lines, and deregulating the underground through a series of public-private partnerships. They cut crime by installing on-board video cameras and boosting the surveillance monitoring of platforms and transfer stations. In short, their system flourishes in a free-market environment.

After all, “public transit is not inherently inferior to the private automobile; it can out-compete the car when and where market forces reign,” says Lawrence Solomon, Toronto Sprawls (2007).

The Calgary Chamber of Commerce suspects most Calgarians want city hall to expand our light rail transit (LRT). And, like the general population, our members complain a barrel of crude oil sells for about $130 and no level of government wants to lower the high taxes paid at the pumps.

Like the rest of the country, Calgarians want world-class transit. Most applaud the notion of getting people out of their cars and relieving the traffic congestion. Yet when city hall recently introduced its best option for the west leg of the LRT, many were opposed and NIMBYism (not-in-my-backyard) raised its head.

Every LRT expansion has seen citizens unhappy with proposed routes, the lack of transparent consultation, the noise, and the alleged decline in property values. In actuality, once the lines were built property values increased. Neighbourhoods appreciate their transit stops and view them as assets to their communities.

The chamber believes that new LRT lines are often derailed by local opposition despite the fact these major infrastructure projects are valuable to the entire city. These land-use decisions are inherently political and frequently determine the popularity of the local alderman.

According to the chamber’s research, particularly contentious zoning applications often take twice as long to be approved as non-politicized applications. Therefore, the city recommends the applicant always undertake extensive community and aldermanic consultation before submitting the application.

Ideally, council’s involvement in the approval process is to set broad policy direction, similar to the structures of the federal and provincial governments. Practically however, the aldermen are often directly involved in approving the land use and zoning applications for their constituents.

Perhaps city hall places too much emphasis on local community consultation (which is important) and ignores the input of citizens from every other community who might park their cars and take transit into the area to work, shop, learn, or play.

After much consideration, the chamber recommends council:

  • Develop a set of citywide consultation protocols for all major land use applications to ensure bigger picture impacts are considered along with local ones.
  • Weigh the valuable contribution from local community groups within the framework of a metropolis consultation and context.
  • Create an electoral reform commission to review the current ward system and investigate moving to a mixed representation model in which council is composed of both ward aldermen and citywide aldermen.

The chamber applauds city hall’s verdict to move forward with the west leg of the LRT. The impacted communities need this infrastructure. It’s also the right decision for Calgary.

With worsening traffic snarls, more smog and escalating gas prices, now is the time to build affordable, efficient public transportation.

Maybe Calgary, like London, can convince more people to park their cars and ride the rails. If the World Madness Institute polled our citizens in a decade would they discover that 89 per cent of Calgarians supported the use of mass transit for themselves?

Heather Douglas is president & CEO of the Calgary Chamber of Commerce For more information on the Chamber’s public transportation recommendations, please see www.calgarychamber.com.

Posted in Energy Probe News, Public Transit | Leave a comment

The Deniers: Our spotless sun

Lawrence Solomon
National Post
May 31, 2008

You probably haven’t heard much of Solar Cycle 24, the current cycle that our sun has entered, and I hope you don’t. If Solar Cycle 24 becomes a household term, your lifestyle could be taking a dramatic turn for the worse.

That of your children and their children could fare worse still, say some scientists, because Solar Cycle 24 could mark a time of profound long-term change in the climate. As put by geophysicist Philip Chapman, a former NASA astronaut-scientist and former president of the National Space Society, “It is time to put aside the global warming dogma, at least to begin contingency planning about what to do if we are moving into another little ice age.”

The sun, of late, is remarkably free of eruptions: It has lost its spots. By this point in the solar cycle, sunspots would ordinarily have been present in goodly numbers. Today’s spotlessness — what alarms Dr. Chapman and others — may be an anomaly of some kind, and the sun may soon revert to form. But if it doesn’t — and with each passing day, the speculation in the scientific community grows that it will not — we could be entering a new epoch that few would welcome.

Sunspots have been well documented throughout human history, starting in the fourth century BC, with written descriptions by Gan De, a Chinese astronomer. In 1128, an English monk, John of Worcester, was the first person known to have drawn sunspots, and after the telescope’s arrival in the early 1600s, observations and drawings became commonplace, including by such luminaries as Galileo Galilei. Then, to the astonishment of astronomers, they saw the sunspots diminish and die out altogether.

This was the case during the Little Ice Age, a period starting in the 15th or 16th century and lasting centuries, says NASA’s Goddard Space Centre, which links the absence of sunspots to the cold that then descended on Earth. During the coldest part of the Little Ice Age, a time known as the Maunder Minimum (named after English astronomer Edward Maunder), astronomers saw only about 50 sunspots over a 30-year period, less than one half of 1% of the sunspots that would normally have been expected. Other Minimums — times of low sunspot activity — also corresponded to times of unusual cold.

The consequences of the Little Ice Age, because they occurred in relatively recent times, have come down to us through literature and the arts as well as from historians and scientists, government and business records. When Shakespeare wrote of “lawn as white as driven snow,” he had first-hand experience — Europe was bitterly cold in his day, a sharp contrast to the very warm weather that preceded his birth. During the Little Ice Age, the River Thames froze over, the Dutch developed the ice skate and the great artists of the day learned to love a new genre: the winter landscape.

In what had been a warm Europe , adaptations were not all happy: Growing seasons in England and Continental Europe generally became short and unreliable, which led to shortages and famine. These hardships were nothing compared to the more northerly countries: Glaciers advanced rapidly in Greenland, Iceland, Scandinavia and North America, making vast tracts of land uninhabitable. The Arctic pack ice extended so far south that several reports describe Eskimos landing their kayaks in Scotland. Finland’s population fell by one-third, Iceland’s by half, the Viking colonies in Greenland were abandoned altogether, as were many Inuit communities. The cold in North America spread so far south that, in the winter of 1780, New York Harbor froze, enabling people to walk from Manhattan to Staten Island.

In the same way that the Earth shivered when sunspots disappeared, the Earth warmed when sunspot activity became pronounced. The warm period about 1000 years ago known as the Medieval Warm Period — a time of bounty in which grapes grew in England and Greenland was colonized — also was a time of high sunspot activity, called the Medieval Maximum. Since 1900, Earth has experienced what astronomers call “the Modern Maximum” — the 20th century has again been a time of high sunspot activity.

But the 1900s are gone, along with the high temperatures that accompanied them. The last 10 years have seen no increase in temperatures — they reached a plateau and then remained there — and the last year saw a precipitous decline. How much lower and for how long the temperatures will fall, if at all, no one yet knows — the science is far from settled on what drives climate.

But many are watching the sun for answers, and for good reason. Several renowned scientists have been predicting for some time that the world could enter a period of cooling right around now, with consequences that could be dire. “The next little ice age would be much worse than the previous one and much more harmful than anything warming may do,” believes Dr. Chapman. “There are many more people now and we have become dependent on a few temperate agricultural areas, especially in the U.S. and Canada. Global warming would increase agricultural output, but global cooling will decrease it.”

We are now at the beginning of Solar Cycle 24, so named because it is the 24th consecutive cycle that astronomers have listed, starting with the first cycle that began in March, 1755, and ended in June, 1766. Each cycle lasts an average of approximately 11 years; each is marked by sunspots that first erupt in the mid latitudes of the sun, and then, over the course of the 11 years, erupt progressively toward the sun’s equator; each is marked by a change in the polarity of the sun’s hemispheres; each changes the temperature on Earth in ways that humans don’t fully understand, but cannot in all honesty deny.

Photo: The spotless Sun, as it appeared on May 30 at 12:48 p.m. The Sun’s spotlessness is giving rise to speculation of another Little Ice Age. (Solarcycle24.com)

To read other articles in The Deniers series, see: http://energy.probeinternational.org/climate-change/the-deniers

Posted in Costs, Benefits and Risks, Energy Probe News, Global Cooling | 1 Comment

Thou shalt not ask awkward questions (review of The Deniers)

Mick Hume
Spiked-online.com
May 30, 2008

“Scepticism and the questioning of orthodoxies must be an integral part of the scientific process.”
A new book shows that some of those labelled ‘the deniers’ of global warming, and depicted as oil-funded crooks, are in fact sensible, respectable scientists. Why have they been made into heretics?

This short book shows how the mainstream view of man-made global warming has become an orthodoxy that cannot be questioned, its much-publicised ‘scientific consensus’ sustained in part by pressure, the sidelining of even authoritative dissent, and the politically-motivated machinations of the government-led Intergovernmental Panel on Climate Change. Some of the shriller critics of environmentalism claim that it has become a religion. I think that goes too far — for a start, the green view of humanity is too toxic to offer anything like transcendence. But it is clear that those who question the orthodoxy on man-made global warming are now treated automatically as heretics. To be branded a ‘denier’ is to be accused of the modern secular equivalent of blasphemy.

We need not be scientists, or endorse any of the ‘alternative’ theories of climate change, to appreciate the importance of the ‘deniers’ debate. (Nor do we need to endorse Solomon’s own green notions, such as his view of the dangers of developing nuclear power to cut carbon emissions.) The expertise he presents demonstrates that climatology is a complex and multi-faceted science in which there is no genuine consensus, and indeed no real over-arching theory at all. But then, as one of the deniers, Dr Robert Carter, says, ‘science is not, nor ever has been, about consensus, but about experimental and observational data and testable hypotheses’.

Read more

Mick Hume is editor-at-large of spiked.

The Deniers, by Lawrence Solomon is published by Richard Vigilante Books. (Buy this book from Amazon).

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The Deniers: Global Warming advocate rethinks position

http://www.dnronline.com (The Daily News-Record)
May 27, 2008

Lawrence Solomon works for Energy Probe, a Canadian environmentalist group dedicated to opposing the nuclear-power industry. Mr. Solomon also writes a weekly column for Toronto’s National Post and is aligned to the Urban Renaissance Institute. One, therefore, might consider him a tried-and-true believer in the concept of man-made global warming. And yes, he was.

The key word in the preceding paragraph is, of course, “was.” Some time ago, Mr. Solomon decided to probe the minds of scientists derisively called “The Deniers” (think “Holocaust deniers”) because they refused to join the gadarene rush to the supposed global warming “consensus.” After months of interviews and writing, here is what Mr. Solomon has concluded.

Read on

The News-Record publishes over 32,000 copies a day for readers in four Virginia counties and three counties in West Virginia. The total estimated readership daily is more than 80,000 (based on the nationally-proven formula of about 2.5 readers per issue).

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McCain's French Romance

Carl Pope
Huffington Post
May 22, 2008

Senator John McCain’s nuclear stance comes under scrutiny this week from Carl Pope of the Sierra Club environmental group in his column for the Huffington Post blog. Pope asks how McCain can justify his double standard of opposing subsidies for solar power on one hand, and defending his support for an increase in subsidies for nuclear power, on the other. In his critique of McCain, Pope draws on Lawrence Solomon‘s recent article, The limits to nuclear: McCain shouldn’t try to follow French disaster. Writes Pope:

McCain "likes to claim that [nuclear] is a proven clean technology, and cites as evidence France, where he claims nuclear power generates 80 percent of the electricity. … But a recent analysis by Lawrence Solomon shows that citing the French experience is yet another example of McCain having failed to keep up with events.

"Solomon explains the sordid story of France’s nuclear romance. It’s technical, but if you want to know why nuclear power is — even for its wildest fans — a limited part of our energy future, worth reading."



Source

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Carbo-charged nuclear

Lawrence Solomon
FP Comment
May 21, 2008

Nuclear power has been an economic failure, despite being larded with subsidies and shorn of liabilities that face its competitors. Oil price hikes have not made it economic, either.

But the nuclear power industry may soon break through the economic barrier, according to an analysis from the U.S. Congressional Budget Office. Nuclear Power’s Role in Generating Electricity, a study released this month, explains that “the attractiveness of financing a new nuclear power plant depends on investors’ expectations about the costs of emitting carbon dioxide over the operating life of that plant. To the extent that carbon dioxide charges are expected, investment in new nuclear capacity would be more attractive relative to both the construction of new fossil-fuel capacity and the continued use of existing fossil-fuel capacity.”

The CBO adds that “a survey conducted by Cambridge Energy Research Associates in 2006 found that about 80% of utility executives expected a carbon dioxide charge to be implemented within the next 10 years.”

With a carbon-dioxide tax that exceeds $20 per metric ton, the CBO found, a new nuclear plant becomes more economic than a new coal plant. Should the tax exceed $45 per metric ton, nuclear bests natural gas, too. A carbon tax hits coal especially hard: It emits nearly a metric ton of carbon dioxide for every megawatt hour of electricity produced, compared to half a ton for natural gas.

Lawrence Solomon is executive director of Energy Probe and author of The Deniers: The world-renowned scientists who stood up against global warming hysteria, political persecution, and fraud.

Posted in Energy Probe News, Nuclear Economics | Tagged | Leave a comment

Unconventional wisdom

Brit Hume
Special Report with Brit Hume
May 21, 2008

The Deniers received special mention on the “Political Grapevine” segment of “Special Report with Brit Hume”:

“A man described as an anti-nuclear, 1970s peace activist who opposes subsidies to the oil industry has written a book challenging conventional wisdom about global warming. Lawrence Solomon lays out arguments on both sides — including information that often goes unreported in the mainstream media.

“The book is called The Deniers: The world-renowned scientists who stood up against global warming hysteria, political persecution, and fraud* *And those who are too fearful to do so.

“Among its topics, the fact that while some ice is melting at the North Pole, the South Pole is actually getting colder. Solomon also writes that while many scientists believe the sun plays a part in climate change, the U.N.’s global warming panel refuses to even consider it.”

The Brit Hume “Special Report” is a highly rated political program which airs weekdays on the Fox News Channel.

Source

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